Protein Engineer
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Summary
Responsibility:
Developing LiliumX’s modular bispecific antibody platform
Requirement:
Experience with protein engineering
Salary:
Competitive London band
Starting date:
ASAP
Location:
Westbourne Studios, London
ABOUT US
LiliumX are a recent University of Oxford spinout that drives innovation in bispecific antibody R&D against cancer. We believe that current bispecific antibody R&D is outdated and focused only on limited known biology. We break free of this limitation by using our highly modular and high-throughput protein platform to discover novel target combinations to make first-in-class bispecific antibodies with entirely new mechanisms of action.
We are backed by mission-driven investors including Y Combinator, Hoxton Ventures, Magnet Ventures, and Acequia Capital. We are disrupting the field of bispecific antibodies and we’re looking for like-minded people to join our efforts to create an impact; we are looking for you.
THE ROLE
During your time with us, you will be involved in:
- Designing and selecting suitable protein mutations through in silico methods for increased stability and/or function
- Producing proteins following DNA cloning from bacterial or mammalian cells
- Designing and analysing in vivo animal studies
- Analysing protein characteristics through biochemical and biophysical methodologies
- Suggesting and implementing novel ideas related to LiliumX’s protein engineering procedure and
facility expansion - Supervising technical staff and junior researchers / placement students
- Working collaboratively with the protein production and cell biology team
- Interfacing with scaling of LiliumX’s protein engineering process
- Supporting grant applications, article publications and patent filing
WHO YOU ARE
We are looking for candidates with:
- A PhD (or related) degree in a cell biology-related discipline
- Experience in working with molecular biology techniques, including DNA cloning and protein purification
- Experience in computational protein engineering using
applications such as Rosetta modelling or similar - Motivation to challenge and learn new skills and knowledge
Not required but helpful attributes include:
- Knowledge in open-source software, bioinformatics tools
and programming languages such as Python - Experience in using an automated liquid handler, such as Opentrons
- Experience in modern cloning approaches and FPLC protein purification
- Prior experience in protein directed evolution
- Prior working experience in industry
WHAT WE OFFER
- Competitive salary
- Share scheme
- Pension
- Flexible hours
- Chance to make a direct impact
to the bispecific antibody field
DIVERSITY AND INCLUSION
Our science knows no boundaries and neither do our employment criteria.. We welcome applicants from any background without discrimination on the basis of race, colour, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.
HOW TO APPLY
Email us with your CV and your interest in applying at
careers@liliumx.com
